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Redefining what's possible in molecular analysis

At Isospec, we specialize in molecular identification services tailored for biotech product development and biomarker discovery.

Glycan Analysis
Early Access

Glycan analysis for infant nutrition and prebiotics

Glycan characterization plays a critical role in the development of nutritional products. We provide the accurate data you need to develop your processes, optimize your design, identify impurities, and bring the quality of your products to the next level.

Use Cases

Human milk oligosaccharide panel

Unlock new insights into infant nutrition by leveraging our exclusive and continuously growing database of 50+ HMO structures measured directly from human milk samples.

Using our existing database of glycans and glycan fragments, we can identify new HMOs,covering more than 200 structures.

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Glycan fermentation products

Identify fermentation products and impurities to generate insights into your production process and move forward with certainty.

Beyond our existing database, our structural elucidation workflows can identify glycans, even when analytical standards are not available!

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Glycan discovery

Discover new glycans and unlock the potential of your products for nutritional and medical applications.

Our structural elucidation package relies on the unique combination of isomer separation, MS/MS and CIRIS to generate structural data with unprecedented accuracy, covering the whole glycome.

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Advancing Drug and Therapeutic Characterization with Precision and Reliability

Determining the glycosylation of monoclonal antibodies and identifying small molecule metabolites are critical issues in drug development. Using a combination of LC-MS and cryogenic infrared ion spectroscopy (CIRIS) we can rapidly identify all molecules of interest in your samples and translate this information into actionable insights to help you optimize your production and move forward with certainty in your drug approval process.

Use Cases

Monoclonal antibody glycosylation analysis

Make sure you have the right glycosylation pattern for optimal performance and stability of your products. Slight changes in the cell culture environment can drastically influence the glycosylation of your biotherapeutics, favoring certain glycoforms over others, which can affect a drug’s efficacy. Traditional glycosylation analysis typically focuses on general trends such as degree of fucosylation and sialylation without identifying the precise isomeric structure, often missing out on crucial insights with regards to the manufacturing process and the properties of the drug. Our unique technology unlocks new insights into your therapeutics and production processes by diving deeper into protein glycosylation, identifying the structure of N- and O-glycans at the isomer level.

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Small drug metabolite identification

Identifying the exact structure of relevant drug metabolites early in the development process allows to have a comprehensive understanding of drug metabolism and move forward with certainty to accelerate the approval process.

We put the unique combination of our analytical technologies at the service of your metabolite identification to allow for the rapid and confident identification of new molecules.

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Therapeutic Characterization
Early Access
Biomarker Discovery
Early Access

Bring your biomarker discovery to the next level

The future of biomarker discovery is dynamic! Current solutions are limited to existing libraries that cover only a small fraction of molecular space and hence are prone to misassignments, which can lead to false discoveries. Our robust metrics unlock a new realm of possibilities and enable groundbreaking discoveries.

Isospec unlocks unlimited access to the glycome and metabolome. We combine well established analytical tools such as LC-MS with our proprietary CIRIS technology, integrate them with automation for sample handling, and use AI tools to generate actionable insights.

Use Cases

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Project Definition

We define the project together, order needed consumables that are not already available in our applications lab, and create the database to start generating insights.

Measurements

Once we receive your samples we use our in-house instruments, including LC-MS, MS/MS, and our exclusive CIRIS technology to uncover the identity of the molecules of interest.

Data interpretation

The data we generate is processed using our ML tools. We then either use our exclusive database and / or perform computations to reveal molecular identities and generate insights into you products and research.

Reporting

We then compile the findings in a report that summarizes the most important findings. We meet one last time to close the project. Raw data can be available in under 24h upon request.

Enhance your research

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Discover how Isospec can help you make the best out your research and move forward with certainty.

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Discover how Isospec can help you make the best out your research and move forward with certainty.

Revolutionizing molecular identification

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